Varaico: Literature-Extracted Genetic Variants

Gene:DRD4
Variant:p.R252G

DRD4

361 papers

RefSeq Summary

This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkin...

Pfam Domains

7tm_1aa 51–400UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

dopamine receptor D4

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
5 papers
NM_000797.4
p.R252G
c.754C>G
Surrounding Variants
1 paper
NM_000797.4
p.R252S
c.754C>A
1 paper
NM_000797.4
p.R252P
c.755G>C
1 paper
NM_000797.4
p.P251S
c.751C>T
1 paper
NM_000797.4
p.L253L
c.759C>T
1 paper
NM_000797.4
p.Q255P
c.764A>C
1 paper
NM_000797.4
p.T247ins16
c.739_740ins48
2 papers
NM_000797.4
p.T247P
c.739A>C
1 paper
NM_000797.4
p.S245A
c.733T>G
1 paper
NM_000797.4
p.C262C
c.786T>C
1 paper
NM_000797.4
p.A263V
c.788C>T
1 paper
NM_000797.4
p.P265P
c.795C>A
1 paper
NM_000797.4
p.P238R
c.713C>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."