Varaico: Literature-Extracted Genetic Variants

Gene:DRD4
Variant:p.G272D

DRD4

361 papers

RefSeq Summary

This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkin...

Pfam Domains

7tm_1aa 51–400UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

dopamine receptor D4

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000797.4
p.G272D
c.815G>A
Surrounding Variants
1 paper
NM_000797.4
p.G272R
c.814G>C
2 papers
NM_000797.4
p.R271P
c.812G>C
1 paper
NM_000797.4
p.R271W
c.811C>T
1 paper
NM_000797.4
p.P273P
c.819C>T
1 paper
NM_000797.4
p.G275G
c.825C>T
1 paper
NM_000797.4
p.L269_C274delFs
c.807_820del14
1 paper
NM_000797.4
p.G268S
c.802G>A
1 paper
NM_000797.4
p.G268C
c.802G>T
1 paper
NM_000797.4
p.A266V
c.797C>T
1 paper
NM_000797.4
p.P265P
c.795C>A
1 paper
NM_000797.4
p.P280S
c.838C>T
4 papers
NM_000797.4
p.P280L
c.839C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."