Varaico: Literature-Extracted Genetic Variants

Gene:DUSP1
Variant:p.T333A

DUSP1

98 papers

RefSeq Summary

The protein encoded by this gene is a phosphatase with dual specificity for tyrosine and threonine. The encoded protein can dephosphorylate MAP kinase MAPK1/ERK2, which results in its involvement in s...

Pfam Domains

Rhodaneseaa 9–131UCSCRhodanese-like domain
DSPcaa 181–311UCSCDual specificity phosphatase, catalytic domain

Gene Aliases

HGNC Name

dual specificity phosphatase 1

HGNC Previous Symbol

PTPN10

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004417.4
p.T333A
c.997A>G
Surrounding Variants
1 paper
NM_004417.4
p.D330N
c.988G>A
1 paper
NM_004417.4
p.V338M
c.1012G>A
1 paper
NM_004417.4
p.F341L
c.1021T>C
3 papers
NM_004417.4
p.A325T
c.973G>A
1 paper
NM_004417.4
p.F341L
c.1023C>G
1 paper
NM_004417.4
p.F341L
c.1023C>A
1 paper
NM_004417.4
p.E320V
c.959A>T
1 paper
NM_004417.4
p.P315P
c.945G>A
1 paper
NM_004417.4
p.S310S
c.930C>A
1 paper
NM_004417.4
p.I361V
c.1081A>G
1 paper
NM_004417.4
p.R278*
c.832C>T
1 paper
NM_004417.4
p.L270R
c.809T>G
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