Varaico: Literature-Extracted Genetic Variants

Gene:DUSP1
Variant:p.E112A

DUSP1

98 papers

RefSeq Summary

The protein encoded by this gene is a phosphatase with dual specificity for tyrosine and threonine. The encoded protein can dephosphorylate MAP kinase MAPK1/ERK2, which results in its involvement in s...

Pfam Domains

Rhodaneseaa 9–131UCSCRhodanese-like domain
DSPcaa 181–311UCSCDual specificity phosphatase, catalytic domain

Gene Aliases

HGNC Name

dual specificity phosphatase 1

HGNC Previous Symbol

PTPN10

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004417.4
p.E112A
c.335A>C
Surrounding Variants
1 paper
NM_004417.4
p.D99_A115del0
c.296_343del48
1 paper
NM_004417.4
p.A106T
c.316G>A
1 paper
NM_004417.4
p.A105G
c.314C>G
1 paper
NM_004417.4
p.G123Splc
c.367+8C>G
1 paper
NM_004417.4
p.A92T
c.274G>A
1 paper
NM_004417.4
p.V84E
c.251T>A
1 paper
NM_004417.4
p.E70K
c.208G>A
1 paper
NM_004417.4
p.P67P
c.201C>A
1 paper
NM_004417.4
p.H64Y
c.190C>T
4 papers
NM_004417.4
p.M60I
c.180G>T
4 papers
NM_004417.4
p.M60I
c.180G>C
4 papers
NM_004417.4
p.M60I
c.180G>A
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."