Varaico: Literature-Extracted Genetic Variants

Gene:DUSP1
Variant:p.E19V

DUSP1

98 papers

RefSeq Summary

The protein encoded by this gene is a phosphatase with dual specificity for tyrosine and threonine. The encoded protein can dephosphorylate MAP kinase MAPK1/ERK2, which results in its involvement in s...

Pfam Domains

Rhodaneseaa 9–131UCSCRhodanese-like domain
DSPcaa 181–311UCSCDual specificity phosphatase, catalytic domain

Gene Aliases

HGNC Name

dual specificity phosphatase 1

HGNC Previous Symbol

PTPN10

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_004417.4
p.E19V
c.56A>T
Surrounding Variants
1 paper
NM_004417.4
p.G18G
c.54G>A
3 papers
NM_004417.4
p.C24Y
c.71G>A
1 paper
NM_004417.4
p.G12V
c.35G>T
1 paper
NM_004417.4
p.G12D
c.35G>A
2 papers
NM_004417.4
p.F33C
c.98T>G
1 paper
NM_004417.4
p.A34V
c.101C>T
1 paper
NM_004417.4
p.N36Y
c.106A>T
1 paper
NM_004417.4
p.N36H
c.106A>C
1 paper
NM_004417.4
p.G38G
c.114C>A
1 paper
NM_004417.4
p.H39N
c.115C>A
1 paper
NM_004417.4
p.F33_H39delFs
c.99_115del17
1 paper
NM_004417.4
p.I40I
c.120C>T
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