Varaico: Literature-Extracted Genetic Variants

Gene:DUSP2
Variant:p.C257S

DUSP2

118 papers

RefSeq Summary

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/thre...

Pfam Domains

Rhodaneseaa 15–138UCSCRhodanese-like domain
DSPcaa 180–310UCSCDual specificity phosphatase, catalytic domain

Gene Aliases

HGNC Name

dual specificity phosphatase 2

HGNC Alias Symbol

PAC-1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_004418.4
p.C257S
c.769T>A
Surrounding Variants
3 papers
NM_004418.4
p.C257S
c.770G>C
1 paper
NM_004418.4
p.R252W
c.754C>T
1 paper
NM_004418.4
p.G251D
c.752G>A
1 paper
NM_004418.4
p.R263H
c.788G>A
1 paper
NM_004418.4
p.G250R
c.748G>C
1 paper
NM_004418.4
p.G250R
c.748G>A
1 paper
NM_004418.4
p.S249I
c.746G>T
1 paper
NM_004418.4
p.S249N
c.746G>A
1 paper
NM_004418.4
p.A265V
c.794C>T
1 paper
NM_004418.4
p.A265D
c.794C>A
1 paper
NM_004418.4
p.I267insFs
c.800_801ins20
1 paper
NM_004418.4
p.I267fs
c.799_800fs
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."