Varaico: Literature-Extracted Genetic Variants

Gene:DUSP2
Variant:p.T158I

DUSP2

118 papers

RefSeq Summary

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/thre...

Pfam Domains

Rhodaneseaa 15–138UCSCRhodanese-like domain
DSPcaa 180–310UCSCDual specificity phosphatase, catalytic domain

Gene Aliases

HGNC Name

dual specificity phosphatase 2

HGNC Alias Symbol

PAC-1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_004418.4
p.T158I
c.473C>T
Surrounding Variants
1 paper
NM_004418.4
p.T158T
c.474C>G
1 paper
NM_004418.4
p.K157T
c.470A>C
1 paper
NM_004418.4
p.S159S
c.477C>T
1 paper
NM_004418.4
p.R160H
c.479G>A
1 paper
NM_004418.4
p.T154I
c.461C>T
1 paper
NM_004418.4
p.T154R
c.461C>G
1 paper
NM_004418.4
p.S161_D162del1
c.482_484delCGG
1 paper
NM_004418.4
p.P153S
c.457C>T
3 papers
NM_004418.4
p.P152S
c.454C>T
1 paper
NM_004418.4
p.A165S
c.493G>T
2 papers
NM_004418.4
p.A165P
c.493G>C
2 papers
NM_004418.4
p.A165T
c.493G>A
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."