Varaico: Literature-Extracted Genetic Variants

Gene:DUSP2
Variant:p.C143S

DUSP2

118 papers

RefSeq Summary

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/thre...

Pfam Domains

Rhodaneseaa 15–138UCSCRhodanese-like domain
DSPcaa 180–310UCSCDual specificity phosphatase, catalytic domain

Gene Aliases

HGNC Name

dual specificity phosphatase 2

HGNC Alias Symbol

PAC-1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004418.4
p.C143S
c.428G>C
Surrounding Variants
2 papers
NM_004418.4
p.C143F
c.428G>T
5 papers
NM_004418.4
p.C143Y
c.428G>A
1 paper
NM_004418.4
p.C143G
c.427T>G
1 paper
NM_004418.4
p.C143S
c.427T>A
1 paper
NM_004418.4
p.C143C
c.429C>T
3 papers
NM_004418.4
p.C143W
c.429C>G
1 paper
NM_004418.4
p.S144C
c.431C>G
1 paper
NM_004418.4
p.D141H
c.421G>C
1 paper
NM_004418.4
p.A146T
c.436G>A
1 paper
NM_004418.4
p.P140fs
c.418_419fs
3 papers
NM_004418.4
p.G137D
c.410G>A
1 paper
NM_004418.4
p.G137S
c.409G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."