Varaico: Literature-Extracted Genetic Variants

Gene:DUSP2
Variant:p.Q136P

DUSP2

118 papers

RefSeq Summary

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/thre...

Pfam Domains

Rhodaneseaa 15–138UCSCRhodanese-like domain
DSPcaa 180–310UCSCDual specificity phosphatase, catalytic domain

Gene Aliases

HGNC Name

dual specificity phosphatase 2

HGNC Alias Symbol

PAC-1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004418.4
p.Q136P
c.407A>C
Surrounding Variants
1 paper
NM_004418.4
p.Q136*
c.406C>T
1 paper
NM_004418.4
p.G137S
c.409G>A
3 papers
NM_004418.4
p.G137D
c.410G>A
1 paper
NM_004418.4
p.G134V
c.401G>T
3 papers
NM_004418.4
p.G134A
c.401G>C
6 papers
NM_004418.4
p.G134D
c.401G>A
1 paper
NM_004418.4
p.F132C
c.395T>G
1 paper
NM_004418.4
p.P140fs
c.418_419fs
1 paper
NM_004418.4
p.D141H
c.421G>C
3 papers
NM_004418.4
p.G131D
c.392G>A
2 papers
NM_004418.4
p.G130R
c.388G>C
3 papers
NM_004418.4
p.G130Splc
c.389-1G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."