Varaico: Literature-Extracted Genetic Variants

Gene:DUSP2
Variant:p.H116P

DUSP2

118 papers

RefSeq Summary

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/thre...

Pfam Domains

Rhodaneseaa 15–138UCSCRhodanese-like domain
DSPcaa 180–310UCSCDual specificity phosphatase, catalytic domain

Gene Aliases

HGNC Name

dual specificity phosphatase 2

HGNC Alias Symbol

PAC-1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004418.4
p.H116P
c.347A>C
Surrounding Variants
1 paper
NM_004418.4
p.L115Q
c.344T>A
2 papers
NM_004418.4
p.L115fs
c.343_344fs
1 paper
NM_004418.4
p.T118I
c.353C>T
1 paper
NM_004418.4
p.A120E
c.359C>A
1 paper
NM_004418.4
p.G121fs
c.361_362fs
2 papers
NM_004418.4
p.L111V
c.331C>G
1 paper
NM_004418.4
p.L110L
c.330G>A
1 paper
NM_004418.4
p.P122L
c.365C>T
1 paper
NM_004418.4
p.P122delins
c.364_365delinsTT
2 papers
NM_004418.4
p.L115_P122delFs
c.344_365del22
1 paper
NM_004418.4
p.T123S
c.367A>T
1 paper
NM_004418.4
p.T123I
c.368C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."