Varaico: Literature-Extracted Genetic Variants

Gene:DUSP2
Variant:p.D92N

DUSP2

118 papers

RefSeq Summary

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/thre...

Pfam Domains

Rhodaneseaa 15–138UCSCRhodanese-like domain
DSPcaa 180–310UCSCDual specificity phosphatase, catalytic domain

Gene Aliases

HGNC Name

dual specificity phosphatase 2

HGNC Alias Symbol

PAC-1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004418.4
p.D92N
c.274G>A
Surrounding Variants
1 paper
NM_004418.4
p.L91V
c.271C>G
1 paper
NM_004418.4
p.S95R
c.283A>C
1 paper
NM_004418.4
p.S95R
c.285T>G
1 paper
NM_004418.4
p.S95R
c.285T>A
1 paper
NM_004418.4
p.A96T
c.286G>A
1 paper
NM_004418.4
p.V89_A96del0
c.265_288del24
2 papers
NM_004418.4
p.L85V
c.253C>G
1 paper
NM_004418.4
p.E84D
c.252G>T
1 paper
NM_004418.4
p.E84D
c.252G>C
1 paper
NM_004418.4
p.E84E
c.252G>A
1 paper
NM_004418.4
p.E100D
c.300G>T
1 paper
NM_004418.4
p.E100D
c.300G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."