Varaico: Literature-Extracted Genetic Variants

Gene:DUSP2
Variant:p.W51*

DUSP2

118 papers

RefSeq Summary

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/thre...

Pfam Domains

Rhodaneseaa 15–138UCSCRhodanese-like domain
DSPcaa 180–310UCSCDual specificity phosphatase, catalytic domain

Gene Aliases

HGNC Name

dual specificity phosphatase 2

HGNC Alias Symbol

PAC-1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_004418.4
p.W51*
c.152G>A
Surrounding Variants
3 papers
NM_004418.4
p.W51*
c.153G>A
1 paper
NM_004418.4
p.P50S
c.148C>T
1 paper
NM_004418.4
p.P50T
c.148C>A
1 paper
NM_004418.4
p.P48R
c.143C>G
1 paper
NM_004418.4
p.L54_L55insFs
c.162_163insA
1 paper
NM_004418.4
p.L54L
c.162G>A
1 paper
NM_004418.4
p.L55P
c.164T>C
1 paper
NM_004418.4
p.R57P
c.170G>C
1 paper
NM_004418.4
p.R57_A59delFs
c.171_175del5
1 paper
NM_004418.4
p.R60G
c.178C>G
2 papers
NM_004418.4
p.G61D
c.182G>A
1 paper
NM_004418.4
p.C39*
c.117C>A
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