Varaico: Literature-Extracted Genetic Variants

Gene:DUSP6
Variant:p.F343fs

DUSP6

180 papers

RefSeq Summary

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threo...

Pfam Domains

Rhodaneseaa 19–142UCSCRhodanese-like domain
DSPcaa 214–346UCSCDual specificity phosphatase, catalytic domain

Gene Aliases

HGNC Name

dual specificity phosphatase 6

HGNC Alias Symbols

MKP-3; PYST1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001946.4
p.F343fs
c.1027_1028fs
Surrounding Variants
1 paper
NM_001946.4
p.F343insFs
c.1028_1029insA
3 papers
NM_001946.4
p.T346M
c.1037C>T
1 paper
NM_001946.4
p.T346_L347insFs
c.1038_1039insTT
1 paper
NM_001946.4
p.L347insFs
c.1039_1040insT
1 paper
NM_001946.4
p.G348R
c.1042G>C
1 paper
NM_001946.4
p.G348R
c.1042G>A
1 paper
NM_001946.4
p.Q339R
c.1016A>G
1 paper
NM_001946.4
p.G348fs
c.1042_1043fs
1 paper
NM_001946.4
p.S350fs
c.1048_1049fs
1 paper
NM_001946.4
p.S350delFs
c.1048delT
3 papers
NM_001946.4
p.N355I
c.1064A>T
1 paper
NM_001946.4
p.R356K
c.1067G>A
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."