Varaico: Literature-Extracted Genetic Variants

Gene:DUSP6
Variant:p.D321A

DUSP6

180 papers

RefSeq Summary

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threo...

Pfam Domains

Rhodaneseaa 19–142UCSCRhodanese-like domain
DSPcaa 214–346UCSCDual specificity phosphatase, catalytic domain

Gene Aliases

HGNC Name

dual specificity phosphatase 6

HGNC Alias Symbols

MKP-3; PYST1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001946.4
p.D321A
c.962A>C
Surrounding Variants
1 paper
NM_001946.4
p.D321N
c.961G>A
1 paper
NM_001946.4
p.K327I
c.980A>T
1 paper
NM_001946.4
p.N313insFs
c.938dupA
1 paper
NM_001946.4
p.N313fs
c.937_938fs
1 paper
NM_001946.4
p.Q339R
c.1016A>G
1 paper
NM_001946.4
p.V301I
c.901G>A
1 paper
NM_001946.4
p.S300A
c.898T>G
1 paper
NM_001946.4
p.F343insFs
c.1028_1029insA
1 paper
NM_001946.4
p.F343fs
c.1027_1028fs
1 paper
NM_001946.4
p.S298G
c.892A>G
1 paper
NM_001946.4
p.G296D
c.887G>A
3 papers
NM_001946.4
p.T346M
c.1037C>T
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