Varaico: Literature-Extracted Genetic Variants

Gene:DUSP6
Variant:p.F271S

DUSP6

180 papers

RefSeq Summary

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threo...

Pfam Domains

Rhodaneseaa 19–142UCSCRhodanese-like domain
DSPcaa 214–346UCSCDual specificity phosphatase, catalytic domain

Gene Aliases

HGNC Name

dual specificity phosphatase 6

HGNC Alias Symbols

MKP-3; PYST1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001946.4
p.F271S
c.812T>C
Surrounding Variants
1 paper
NM_001946.4
p.Q270H
c.810G>C
1 paper
NM_001946.4
p.Q270Q
c.810G>A
1 paper
NM_001946.4
p.S269C
c.806C>G
1 paper
NM_001946.4
p.E274G
c.821A>G
1 paper
NM_001946.4
p.S277Y
c.830C>A
1 paper
NM_001946.4
p.H263Y
c.787C>T
1 paper
NM_001946.4
p.D262delFs
c.785delT
1 paper
NM_001946.4
p.F278_D280delFs
c.832_838del7
1 paper
NM_001946.4
p.S277_D280delFs
c.831_838del8
1 paper
NM_001946.4
p.D262N
c.784G>A
1 paper
NM_001946.4
p.P259S
c.775C>T
1 paper
NM_001946.4
p.G232D
c.695G>A
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