Varaico: Literature-Extracted Genetic Variants

Gene:DUSP6
Variant:p.L228V

DUSP6

180 papers

RefSeq Summary

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threo...

Pfam Domains

Rhodaneseaa 19–142UCSCRhodanese-like domain
DSPcaa 214–346UCSCDual specificity phosphatase, catalytic domain

Gene Aliases

HGNC Name

dual specificity phosphatase 6

HGNC Alias Symbols

MKP-3; PYST1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001946.4
p.L228V
c.682T>G
Surrounding Variants
1 paper
NM_001946.4
p.N224K
c.672C>A
1 paper
NM_001946.4
p.G232D
c.695G>A
1 paper
NM_001946.4
p.S202C
c.604A>T
1 paper
NM_001946.4
p.S200T
c.598T>A
1 paper
NM_001946.4
p.G196_P198delFs
c.588_592del5
1 paper
NM_001946.4
p.P259S
c.775C>T
1 paper
NM_001946.4
p.S194P
c.580T>C
1 paper
NM_001946.4
p.D262N
c.784G>A
1 paper
NM_001946.4
p.D262delFs
c.785delT
1 paper
NM_001946.4
p.H263Y
c.787C>T
1 paper
NM_001946.4
p.T192S
c.574A>T
1 paper
NM_001946.4
p.A191G
c.572C>G
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