Varaico: Literature-Extracted Genetic Variants

Gene:DUSP6
Variant:p.S144P

DUSP6

180 papers

RefSeq Summary

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threo...

Pfam Domains

Rhodaneseaa 19–142UCSCRhodanese-like domain
DSPcaa 214–346UCSCDual specificity phosphatase, catalytic domain

Gene Aliases

HGNC Name

dual specificity phosphatase 6

HGNC Alias Symbols

MKP-3; PYST1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001946.4
p.S144P
c.430T>C
Surrounding Variants
7 papers
NM_001946.4
p.S144A
c.430T>G
1 paper
NM_001946.4
p.S144C
c.431C>G
2 papers
NM_001946.4
p.L145R
c.434T>G
1 paper
NM_001946.4
p.L151I
c.451C>A
1 paper
NM_001946.4
p.L151Q
c.452T>A
1 paper
NM_001946.4
p.S154L
c.461C>T
1 paper
NM_001946.4
p.S156S
c.468C>T
1 paper
NM_001946.4
p.S157I
c.470G>T
1 paper
NM_001946.4
p.G169S
c.505G>A
1 paper
NM_001946.4
p.I172I
c.516C>T
1 paper
NM_001946.4
p.D175N
c.523G>A
1 paper
NM_001946.4
p.S177F
c.530C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."