Varaico: Literature-Extracted Genetic Variants

Gene:DUSP6
Variant:p.E112A

DUSP6

180 papers

RefSeq Summary

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threo...

Pfam Domains

Rhodaneseaa 19–142UCSCRhodanese-like domain
DSPcaa 214–346UCSCDual specificity phosphatase, catalytic domain

Gene Aliases

HGNC Name

dual specificity phosphatase 6

HGNC Alias Symbols

MKP-3; PYST1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001946.4
p.E112A
c.335A>C
Surrounding Variants
9 papers
NM_001946.4
p.V114L
c.340G>T
9 papers
NM_001946.4
p.V114L
c.340G>C
1 paper
NM_001946.4
p.N106S
c.317A>G
1 paper
NM_001946.4
p.S103T
c.308G>C
1 paper
NM_001946.4
p.K121N
c.363G>C
1 paper
NM_001946.4
p.S102R
c.306C>G
1 paper
NM_001946.4
p.L122H
c.365T>A
2 papers
NM_001946.4
p.D124G
c.371A>G
1 paper
NM_001946.4
p.E125*
c.373G>T
1 paper
NM_001946.4
p.E125K
c.373G>A
2 papers
NM_001946.4
p.D99G
c.296A>G
1 paper
NM_001946.4
p.Y98H
c.292T>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."