Varaico: Literature-Extracted Genetic Variants

Gene:DUSP6
Variant:p.D99G

DUSP6

180 papers

RefSeq Summary

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threo...

Pfam Domains

Rhodaneseaa 19–142UCSCRhodanese-like domain
DSPcaa 214–346UCSCDual specificity phosphatase, catalytic domain

Gene Aliases

HGNC Name

dual specificity phosphatase 6

HGNC Alias Symbols

MKP-3; PYST1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_001946.4
p.D99G
c.296A>G
Surrounding Variants
1 paper
NM_001946.4
p.Y98H
c.292T>C
1 paper
NM_001946.4
p.S102R
c.306C>G
1 paper
NM_001946.4
p.S103T
c.308G>C
1 paper
NM_001946.4
p.D93_T94del1
c.278_280delTGT
1 paper
NM_001946.4
p.N106S
c.317A>G
1 paper
NM_001946.4
p.T92A
c.274A>G
3 papers
NM_001946.4
p.T87I
c.260C>T
1 paper
NM_001946.4
p.E112A
c.335A>C
1 paper
NM_001946.4
p.R85L
c.254G>T
1 paper
NM_001946.4
p.R85C
c.253C>T
9 papers
NM_001946.4
p.V114L
c.340G>T
9 papers
NM_001946.4
p.V114L
c.340G>C
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