Varaico: Literature-Extracted Genetic Variants

Gene:DUSP6
Variant:p.R85C

DUSP6

180 papers

RefSeq Summary

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threo...

Pfam Domains

Rhodaneseaa 19–142UCSCRhodanese-like domain
DSPcaa 214–346UCSCDual specificity phosphatase, catalytic domain

Gene Aliases

HGNC Name

dual specificity phosphatase 6

HGNC Alias Symbols

MKP-3; PYST1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001946.4
p.R85C
c.253C>T
Surrounding Variants
1 paper
NM_001946.4
p.R85L
c.254G>T
1 paper
NM_001946.4
p.R83Q
c.248G>A
3 papers
NM_001946.4
p.T87I
c.260C>T
2 papers
NM_001946.4
p.E81K
c.241G>A
1 paper
NM_001946.4
p.T92A
c.274A>G
4 papers
NM_001946.4
p.F77I
c.229T>A
1 paper
NM_001946.4
p.D93_T94del1
c.278_280delTGT
1 paper
NM_001946.4
p.P72R
c.215C>G
1 paper
NM_001946.4
p.P72Q
c.215C>A
1 paper
NM_001946.4
p.Y98H
c.292T>C
2 papers
NM_001946.4
p.D99G
c.296A>G
1 paper
NM_001946.4
p.K68M
c.203A>T
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."