Varaico: Literature-Extracted Genetic Variants

Gene:DUSP6
Variant:p.M62V

DUSP6

180 papers

RefSeq Summary

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threo...

Pfam Domains

Rhodaneseaa 19–142UCSCRhodanese-like domain
DSPcaa 214–346UCSCDual specificity phosphatase, catalytic domain

Gene Aliases

HGNC Name

dual specificity phosphatase 6

HGNC Alias Symbols

MKP-3; PYST1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001946.4
p.M62V
c.184A>G
Surrounding Variants
1 paper
NM_001946.4
p.I61_M62insFs
c.183_184insC
3 papers
NM_001946.4
p.M62I
c.186G>T
1 paper
NM_001946.4
p.M62fs
c.184_185fs
3 papers
NM_001946.4
p.M62I
c.186G>C
3 papers
NM_001946.4
p.M62I
c.186G>A
1 paper
NM_001946.4
p.L63Q
c.188T>A
1 paper
NM_001946.4
p.A57V
c.170C>T
1 paper
NM_001946.4
p.N55delFs
c.163delT
1 paper
NM_001946.4
p.K68M
c.203A>T
1 paper
NM_001946.4
p.P72R
c.215C>G
1 paper
NM_001946.4
p.P72Q
c.215C>A
2 papers
NM_001946.4
p.H49L
c.146A>T
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