Varaico: Literature-Extracted Genetic Variants

Gene:DUSP6
Variant:p.W22*

DUSP6

180 papers

RefSeq Summary

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threo...

Pfam Domains

Rhodaneseaa 19–142UCSCRhodanese-like domain
DSPcaa 214–346UCSCDual specificity phosphatase, catalytic domain

Gene Aliases

HGNC Name

dual specificity phosphatase 6

HGNC Alias Symbols

MKP-3; PYST1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001946.4
p.W22*
c.66G>A
Surrounding Variants
1 paper
NM_001946.4
p.W22*
c.65G>A
1 paper
NM_001946.4
p.L23fs
c.67_68fs
1 paper
NM_001946.4
p.V20M
c.58G>A
1 paper
NM_001946.4
p.E25D
c.75G>T
1 paper
NM_001946.4
p.E25D
c.75G>C
1 paper
NM_001946.4
p.T19T
c.57G>C
1 paper
NM_001946.4
p.Q26H
c.78G>T
1 paper
NM_001946.4
p.Q26H
c.78G>C
1 paper
NM_001946.4
p.S17C
c.49A>T
1 paper
NM_001946.4
p.A11T
c.31G>A
1 paper
NM_001946.4
p.L5insFs
c.14_15insA
1 paper
NM_001946.4
p.R40W
c.118C>T
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."