Home Downloads UCSC Genome Browser Track Email Updates

Varaico: Literature-Extracted Genetic Variants

Include likely false extractions

Gene:DUSP8

DUSP8

49 papers

RefSeq Summary

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threo...

Pfam Domains

Rhodaneseaa 12–132UCSCRhodanese-like domain

DSPcaa 168–299UCSCDual specificity phosphatase, catalytic domain

Gene Aliases

HGNC Name

dual specificity phosphatase 8

HGNC Previous Symbol

C11orf81

Papers

Position

RefSeq ID

Protein change

DNA change

Pfam

gnomAD

1–12 of 47 variants

2 papers

chr11:1557318 C>T

NM_004420.3

p.A360T

c.1078G>A

Exome: 0.0% (AC=2, hom=0)Genome: 0.0% (AC=1, hom=0)3 overlapping SVs

1 paper

chr11:1565791 A>C

NM_004420.3

p.D12E

c.36T>G

Rhodanese

Exome: 0.0% (AC=714, hom=0)Genome: 0.0% (AC=57, hom=0)3 overlapping SVs

1 paper

chr11:1565791 A>T

NM_004420.3

p.D12E

c.36T>A

Rhodanese

exact variant not in gnomAD3 overlapping SVs

1 paper

chr11:1565725 G>A

NM_004420.3

p.S34S

c.102C>T

Rhodanese

Exome: 0.0% (AC=4, hom=0)Genome: 0.0% (AC=1, hom=0)3 overlapping SVs

1 paper

chr11:1565701 A>T

NM_004420.3

p.H42Q

c.126T>A

Rhodanese

exact variant not in gnomAD3 overlapping SVs

1 paper

chr11:1565667 G>T

NM_004420.3

p.L54M

c.160C>A

Rhodanese

exact variant not in gnomAD3 overlapping SVs

1 paper

chr11:1565640 T>G

NM_004420.3

p.K63Q

c.187A>C

Rhodanese

exact variant not in gnomAD3 overlapping SVs

1 paper

chr11:1565615 T>C

NM_004420.3

p.Q71R

c.212A>G

Rhodanese

exact variant not in gnomAD3 overlapping SVs

1 paper

chr11:1565604 G>A

NM_004420.3

p.R75C

c.223C>T

Rhodanese

Exome: 0.0% (AC=77, hom=0)Genome: 0.0% (AC=1, hom=0)3 overlapping SVs

1 paper

chr11:1563965 C>T

NM_004420.3

p.V86M

c.256G>A

Rhodanese

Exome: 0.0% (AC=2, hom=0)Genome: n/a3 overlapping SVs

1 paper

chr11:1563955 T>C

NM_004420.3

p.Y89C

c.266A>G

Rhodanese

Exome: 0.0% (AC=0, hom=0)Genome: n/a3 overlapping SVs

1 paper

chr11:1563946 C>T

NM_004420.3

p.S92N

c.275G>A

Rhodanese

Exome: 0.0% (AC=0, hom=0)Genome: n/a3 overlapping SVs

UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."