dynein light chain roadblock-type 1

DNCL2A

DNLC2A

ROBLD1

dynein, cytoplasmic, light polypeptide 2A

roadblock domain containing 1

Dynein light chain roadblock-type 1

Bithoraxoid-like protein

Dynein light chain 2A, cytoplasmic

Dynein-associated protein Km23

Roadblock domain-containing protein 1

This gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts with transforming growth factor-beta, and has been implicated in the regulation of actin modulating proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 12 and 18. [provided by RefSeq, Aug 2013].

Varaico: Literature-Extracted Genetic Variants

DYNLRB1

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Symbol