Varaico: Literature-Extracted Genetic Variants

Gene:E2F2
Variant:p.E420A

E2F2

126 papers

RefSeq Summary

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is...

Pfam Domains

WHD_E2F_TDPaa 130–194UCSCE2F/DP family winged-helix DNA-binding domain
E2F_CC-MBaa 210–304UCSCE2F transcription factor CC-MB domain

Gene Aliases

HGNC Name

E2F transcription factor 2

HGNC Alias Symbol

E2F-2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004091.4
p.E420A
c.1259A>C
Surrounding Variants
1 paper
NM_004091.4
p.G421S
c.1261G>A
1 paper
NM_004091.4
p.I422V
c.1264A>G
1 paper
NM_004091.4
p.S423C
c.1267A>T
1 paper
NM_004091.4
p.Y429C
c.1286A>G
2 papers
NM_004091.4
p.D411N
c.1231G>A
2 papers
NM_004091.4
p.E386K
c.1156G>A
2 papers
NM_004091.4
p.E376D
c.1128G>T
2 papers
NM_004091.4
p.E376D
c.1128G>C
1 paper
NM_004091.4
p.P367delFs
c.1100delG
2 papers
NM_004091.4
p.P362H
c.1085C>A
1 paper
NM_004091.4
p.P361P
c.1083G>C
1 paper
NM_004091.4
p.P361L
c.1082C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."