Varaico: Literature-Extracted Genetic Variants

Gene:E2F2
Variant:p.R246G

E2F2

126 papers

RefSeq Summary

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is...

Pfam Domains

WHD_E2F_TDPaa 130–194UCSCE2F/DP family winged-helix DNA-binding domain
E2F_CC-MBaa 210–304UCSCE2F transcription factor CC-MB domain

Gene Aliases

HGNC Name

E2F transcription factor 2

HGNC Alias Symbol

E2F-2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004091.4
p.R246G
c.736A>G
Surrounding Variants
1 paper
NM_004091.4
p.Y249*
c.747T>G
1 paper
NM_004091.4
p.Y249*
c.747T>A
3 papers
NM_004091.4
p.G259S
c.775G>A
4 papers
NM_004091.4
p.T265I
c.794C>T
1 paper
NM_004091.4
p.P272A
c.814C>G
1 paper
NM_004091.4
p.T239A
c.715A>G
1 paper
NM_004091.4
p.C231_S232del2
c.691_695del6
1 paper
NM_004091.4
p.C231W
c.693C>G
13 papers
NM_004091.4
p.Q226H
c.678G>T
13 papers
NM_004091.4
p.Q226H
c.678G>C
1 paper
NM_004091.4
p.Q226*
c.676C>T
3 papers
NM_004091.4
p.G205R
c.613G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."