Varaico: Literature-Extracted Genetic Variants

Gene:E2F2
Variant:p.I169M

E2F2

126 papers

RefSeq Summary

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is...

Pfam Domains

WHD_E2F_TDPaa 130–194UCSCE2F/DP family winged-helix DNA-binding domain
E2F_CC-MBaa 210–304UCSCE2F transcription factor CC-MB domain

Gene Aliases

HGNC Name

E2F transcription factor 2

HGNC Alias Symbol

E2F-2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004091.4
p.I169M
c.507C>G
Surrounding Variants
1 paper
NM_004091.4
p.R168H
c.503G>A
2 papers
NM_004091.4
p.R168C
c.502C>T
1 paper
NM_004091.4
p.R167Q
c.500G>A
1 paper
NM_004091.4
p.R167W
c.499C>T
1 paper
NM_004091.4
p.T173T
c.519C>G
1 paper
NM_004091.4
p.V175M
c.523G>A
1 paper
NM_004091.4
p.D163N
c.487G>A
1 paper
NM_004091.4
p.G178C
c.532G>T
1 paper
NM_004091.4
p.G178D
c.533G>A
1 paper
NM_004091.4
p.A159T
c.475G>A
1 paper
NM_004091.4
p.R183H
c.548G>A
1 paper
NM_004091.4
p.D154N
c.460G>A
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