Varaico: Literature-Extracted Genetic Variants

Gene:E2F4
Variant:p.D42V

E2F4

137 papers

RefSeq Summary

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is...

Pfam Domains

WHD_E2F_TDPaa 18–83UCSCE2F/DP family winged-helix DNA-binding domain
E2F_CC-MBaa 100–196UCSCE2F transcription factor CC-MB domain

Gene Aliases

HGNC Name

E2F transcription factor 4

HGNC Alias Symbol

E2F-4

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001950.4
p.D42V
c.125A>T
Surrounding Variants
1 paper
NM_001950.4
p.D42H
c.124G>C
3 papers
NM_001950.4
p.L33R
c.98T>G
1 paper
NM_001950.4
p.L32I
c.94C>A
1 paper
NM_001950.4
p.S21_L22insFs
c.63_64ins13
1 paper
NM_001950.4
p.T14A
c.40A>G
2 papers
NM_001950.4
p.G13D
c.38G>A
1 paper
NM_001950.4
p.E3G
c.8A>G
1 paper
NM_001950.4
p.A2G
c.5C>G
1 paper
NM_001950.4
p.A46A
c.138A>G
1 paper
NM_001950.4
p.I71I
c.213C>T
1 paper
NM_001950.4
p.S75A
c.223T>G
1 paper
NM_001950.4
p.I98_E99delFs
c.293_296del4
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."