Varaico: Literature-Extracted Genetic Variants

Gene:E2F6
Variant:p.R179Splc

E2F6

34 papers

RefSeq Summary

This gene encodes a member of a family of transcription factors that play a crucial role in the control of the cell cycle. The protein encoded by this gene lacks the transactivation and tumor suppress...

Pfam Domains

WHD_E2F_TDPaa 64–128UCSCE2F/DP family winged-helix DNA-binding domain
E2F_CC-MBaa 143–237UCSCE2F transcription factor CC-MB domain

Gene Aliases

HGNC Name

E2F transcription factor 6

HGNC Alias Symbol

E2F-6

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_198256.4
p.R179Splc
c.537-8A>C
Surrounding Variants
1 paper
NM_198256.4
p.H189Y
c.565C>T
1 paper
NM_198256.4
p.H195P
c.584A>C
1 paper
NM_198256.4
p.L168delFs
c.504delC
1 paper
NM_001278278.2
p.L68V
c.202C>G
1 paper
NM_198256.4
p.T227I
c.680C>T
1 paper
NM_198256.4
p.I231V
c.691A>G
1 paper
NM_198256.4
p.T253I
c.758C>T
1 paper
NM_198256.4
p.K119N
c.357A>T
1 paper
NM_198256.4
p.V116I
c.346G>A
1 paper
NM_198256.4
p.R101W
c.301C>T
1 paper
NM_198256.4
p.L89F
c.267A>T
1 paper
NM_198256.4
p.L78L
c.234T>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."