Varaico: Literature-Extracted Genetic Variants

EDC3

43 papers

RefSeq Summary

This gene encodes a protein that is important in mRNA degradation. The encoded protein is a component of a decapping complex that promotes efficient removal of the monomethylguanosine (m7G) cap from m...

Pfam Domains

LSM14aa 4–67UCSCScd6-like Sm domain

Edc3_linkeraa 102–194UCSCLinker region of enhancer of mRNA-decapping protein 3

FDFaa 198–301UCSCFDF domain

YjeF_Naa 301–467UCSCYjeF-related protein N-terminus

Gene Aliases

HGNC Name

enhancer of mRNA decapping 3

HGNC Previous Symbol

YJDC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_025083.5

p.I479V

c.1435A>G

Surrounding Variants

1 paper

NM_025083.5

p.Y475F

c.1424A>T

1 paper

NM_025083.5

p.I474I

c.1422C>T

1 paper

NM_025083.5

p.R473H

c.1418G>A

1 paper

NM_025083.5

p.G472D

c.1415G>A

1 paper

NM_025083.5

p.P466S

c.1396C>T

1 paper

NM_025083.5

p.L465L

c.1395G>A

1 paper

NM_025083.5

p.L465insFs

c.1394_1395insC

1 paper

NM_025083.5

p.A508S

c.1522G>T

1 paper

NM_025083.5

p.E450K

c.1348G>A

1 paper

NM_025083.5

p.D443V

c.1328A>T

1 paper

NM_025083.5

p.I442V

c.1324A>G

1 paper

NM_025083.5

p.P423S

c.1267C>T