Varaico: Literature-Extracted Genetic Variants

Gene:EDNRB
Variant:p.W276G

EDNRB

450 papers

RefSeq Summary

The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent va...

Pfam Domains

7tm_1aa 118–387UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

endothelin receptor type B

HGNC Previous Symbols

HSCR2; HSCR

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001122659.3
p.W276G
c.826T>G
Surrounding Variants
3 papers
NM_001122659.3
p.W275*
c.825G>A
1 paper
NM_001122659.3
p.W276*
c.827G>A
60 papers
NM_001122659.3
p.W276C
c.828G>T
59 papers
NM_001122659.3
p.W276C
c.828G>C
3 papers
NM_001122659.3
p.W275*
c.824G>A
1 paper
NM_001122659.3
p.W276*
c.828G>A
1 paper
NM_001122659.3
p.L277L
c.829C>T
1 paper
NM_001122659.3
p.D274D
c.822T>C
11 papers
NM_001122659.3
p.L277L
c.831A>G
NM_001201397.2
p.L367L
c.1101A>G
1 paper
NM_001122659.3
p.D274G
c.821A>G
1 paper
NM_001122659.3
p.F280C
c.839T>G
1 paper
NM_001122659.3
p.K270E
c.808A>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."