Varaico: Literature-Extracted Genetic Variants

Gene:EIF2AK3
Variant:p.T905T

EIF2AK3

596 papers

RefSeq Summary

The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation ...

Pfam Domains

Pkinaseaa 593–676UCSCProtein kinase domain
Pkinaseaa 864–1077UCSCProtein kinase domain

Gene Aliases

HGNC Name

eukaryotic translation initiation factor 2 alpha kinase 3

HGNC Alias Symbols

PEK; PERK

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004836.7
p.T905T
c.2715C>T
Surrounding Variants
1 paper
NM_004836.7
p.I906T
c.2717T>C
1 paper
NM_004836.7
p.C904R
c.2710T>C
1 paper
NM_004836.7
p.E908K
c.2722G>A
1 paper
NM_004836.7
p.R903Q
c.2708G>A
8 papers
NM_004836.7
p.R903*
c.2707C>T
1 paper
NM_004836.7
p.R909I
c.2726G>T
1 paper
NM_004836.7
p.M900I
c.2700G>T
1 paper
NM_004836.7
p.M900I
c.2700G>C
1 paper
NM_004836.7
p.M900I
c.2700G>A
1 paper
NM_004836.7
p.R911K
c.2732G>A
1 paper
NM_004836.7
p.M900V
c.2698A>G
2 papers
NM_004836.7
p.W899C
c.2697G>T
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