Varaico: Literature-Extracted Genetic Variants

Gene:EIF2AK3
Variant:p.T852T

EIF2AK3

596 papers

RefSeq Summary

The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation ...

Pfam Domains

Pkinaseaa 593–676UCSCProtein kinase domain
Pkinaseaa 864–1077UCSCProtein kinase domain

Gene Aliases

HGNC Name

eukaryotic translation initiation factor 2 alpha kinase 3

HGNC Alias Symbols

PEK; PERK

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004836.7
p.T852T
c.2556A>G
Surrounding Variants
1 paper
NM_004836.7
p.T852I
c.2555C>T
1 paper
NM_004836.7
p.T852R
c.2555C>G
1 paper
NM_004836.7
p.A851A
c.2553T>C
1 paper
NM_004836.7
p.L853L
c.2559G>A
1 paper
NM_004836.7
p.A851V
c.2552C>T
1 paper
NM_004836.7
p.S854C
c.2561C>G
1 paper
NM_004836.7
p.I855V
c.2563A>G
1 paper
NM_004836.7
p.E850A
c.2549A>C
1 paper
NM_004836.7
p.E850Q
c.2548G>C
1 paper
NM_004836.7
p.S849F
c.2546C>T
1 paper
NM_004836.7
p.S848F
c.2543C>T
1 paper
NM_004836.7
p.S848T
c.2542T>A
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