Varaico: Literature-Extracted Genetic Variants

Gene:EIF2AK3
Variant:p.K841Q

EIF2AK3

596 papers

RefSeq Summary

The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation ...

Pfam Domains

Pkinaseaa 593–676UCSCProtein kinase domain
Pkinaseaa 864–1077UCSCProtein kinase domain

Gene Aliases

HGNC Name

eukaryotic translation initiation factor 2 alpha kinase 3

HGNC Alias Symbols

PEK; PERK

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004836.7
p.K841Q
c.2521A>C
Surrounding Variants
1 paper
NM_004836.7
p.P842A
c.2524C>G
1 paper
NM_004836.7
p.T838T
c.2514T>G
1 paper
NM_004836.7
p.S844G
c.2530A>G
1 paper
NM_004836.7
p.S844N
c.2531G>A
1 paper
NM_004836.7
p.L837L
c.2511A>G
1 paper
NM_004836.7
p.S844S
c.2532T>C
1 paper
NM_004836.7
p.L837P
c.2510T>C
1 paper
NM_004836.7
p.L837L
c.2509C>T
1 paper
NM_004836.7
p.S845T
c.2534G>C
1 paper
NM_004836.7
p.K836I
c.2507A>T
1 paper
NM_004836.7
p.N835S
c.2504A>G
1 paper
NM_004836.7
p.N835Y
c.2503A>T
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