Varaico: Literature-Extracted Genetic Variants

EIF4G1

305 papers

RefSeq Summary

The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the i...

Pfam Domains

MIF4Gaa 761–989UCSCMIF4G domain

MA3aa 1242–1354UCSCMA3 domain

W2aa 1520–1599UCSCeIF4-gamma/eIF5/eIF2-epsilon

Gene Aliases

HGNC Name

eukaryotic translation initiation factor 4 gamma 1

HGNC Previous Symbol

EIF4F

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

35 papers

NM_198241.3

p.A502V

c.1505C>T

Surrounding Variants

2 papers

NM_198241.3

p.A502G

c.1505C>G

1 paper

NM_198241.3

p.N498Y

c.1492A>T

1 paper

NM_198241.3

p.I491F

c.1471A>T

6 papers

NM_198241.3

p.P486S

c.1456C>T

1 paper

NM_198241.3

p.P485R

c.1454C>G

1 paper

NM_198241.3

p.P485L

c.1454C>T

1 paper

NM_198241.3

p.P485fs

c.1453_1454fs

1 paper

NM_198241.3

p.P485_P486del2

c.1453_1457del6

1 paper

NM_198241.3

p.L483P

c.1448T>C

1 paper

NM_198241.3

p.V507Splc

c.1519+46C>G

1 paper

NM_198241.3

p.E477K

c.1429G>A

1 paper

NM_198241.3

p.E473E

c.1419A>G