Varaico: Literature-Extracted Genetic Variants

EIF4G1

305 papers

RefSeq Summary

The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the i...

Pfam Domains

MIF4Gaa 761–989UCSCMIF4G domain

MA3aa 1242–1354UCSCMA3 domain

W2aa 1520–1599UCSCeIF4-gamma/eIF5/eIF2-epsilon

Gene Aliases

HGNC Name

eukaryotic translation initiation factor 4 gamma 1

HGNC Previous Symbol

EIF4F

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_198241.3

p.D529N

c.1585G>A

Surrounding Variants

1 paper

NM_198241.3

p.D532N

c.1594G>A

1 paper

NM_004953.5

p.E329G

c.986A>G

3 papers

NM_198241.3

p.E525del1

c.1573_1574delGAG

1 paper

NM_198241.3

p.K519_K523delFs

c.1555_1568del14

1 paper

NM_198241.3

p.K517fs

c.1549_1550fs

1 paper

NM_198241.3

p.I518_N522delFs

c.1552_1565del14

1 paper

NM_198241.3

p.R516W

c.1546C>T

1 paper

NM_198241.3

p.V511M

c.1531G>A

1 paper

NM_198241.3

p.V507V

c.1521G>A

2 papers

NM_198241.3

p.V507Splc

c.1520-22T>C

NM_001194947.2

p.V514Splc

c.1541-22T>C

1 paper

NM_198241.3

p.A537V

c.1610C>T

1 paper

NM_198241.3

p.P539L

c.1616C>T