Varaico: Literature-Extracted Genetic Variants

EIF4G1

305 papers

RefSeq Summary

The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the i...

Pfam Domains

MIF4Gaa 761–989UCSCMIF4G domain

MA3aa 1242–1354UCSCMA3 domain

W2aa 1520–1599UCSCeIF4-gamma/eIF5/eIF2-epsilon

Gene Aliases

HGNC Name

eukaryotic translation initiation factor 4 gamma 1

HGNC Previous Symbol

EIF4F

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_182917.4

p.R1217H

c.3650G>A

NM_198241.3

p.R1216H

c.3647G>A

Surrounding Variants

2 papers

NM_182917.4

p.R1217C

c.3649C>T

NM_198241.3

p.R1216C

c.3646C>T

1 paper

NM_182917.4

p.G1218R

c.3652G>A

1 paper

NM_198241.3

p.R1218W

c.3652C>T

1 paper

NM_198241.3

p.R1218R

c.3654G>C

1 paper

NM_198241.3

p.A1220A

c.3660C>T

1 paper

NM_198241.3

p.T1211T

c.3633G>A

1 paper

NM_198241.3

p.S1209fs

c.3625_3626fs

1 paper

NM_198241.3

p.K1206K

c.3618G>A

51 papers

NM_198241.3

p.R1205H

c.3614G>A

NM_182917.4

p.R1206H

c.3617G>A

4 papers

NM_198241.3

p.R1205C

c.3613C>T

1 paper

NM_198241.3

p.L1204L

c.3610C>T

15 papers

NM_198241.3

p.R1197W

c.3589C>T

NM_182917.4

p.R1198W

c.3592C>T