Varaico: Literature-Extracted Genetic Variants

EIF5B

164 papers

RefSeq Summary

Accurate initiation of translation in eukaryotes is complex and requires many factors, some of which are composed of multiple subunits. The process is simpler in prokaryotes which have only three init...

Pfam Domains

GTP_EFTUaa 629–844UCSCElongation factor Tu GTP binding domain

IF-2aa 957–1070UCSCTranslation-initiation factor 2

GTP_EFTU_D4aa 1090–1183UCSCElongation factor Tu domain 4

Gene Aliases

HGNC Name

eukaryotic translation initiation factor 5B

HGNC Alias Symbols

IF2; KIAA0741; DKFZp434I036; FLJ10524

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_015904.4

p.E176V

c.527A>T

Surrounding Variants

1 paper

NM_015904.4

p.N181H

c.541A>C

1 paper

NM_015904.4

p.E165delFs

c.493delG

1 paper

NM_015904.4

p.N203insFs

c.608dupA

1 paper

NM_015904.4

p.N203fs

c.607_608fs

1 paper

NM_015904.4

p.G209D

c.626G>A

2 papers

NM_015904.4

p.D141A

c.422A>C

1 paper

NM_015904.4

p.D140A

c.419A>C

1 paper

NM_015904.4

p.D139H

c.415G>C

1 paper

NM_015904.4

p.S137_D138del1

c.411_413delTGA

1 paper

NM_015904.4

p.S137_D138del2

c.409_413del6

1 paper

NM_015904.4

p.A221D

c.662C>A

1 paper

NM_015904.4

p.S222A

c.664T>G