ELAV like RNA binding protein 3

PLE21

DKFZp547J036

HUCL

MGC20653

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)

ELAV like neuron-specific RNA binding protein 3

Hu antigen C

paraneoplastic limbic encephalitis antigen 21

paraneoplastic cerebellar degeneration-associated antigen

ELAV-like protein 3

Hu-antigen C

Paraneoplastic cerebellar degeneration-associated antigen

Paraneoplastic limbic encephalitis antigen 21

A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Varaico: Literature-Extracted Genetic Variants

ELAVL3

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Alias Symbols