Varaico: Literature-Extracted Genetic Variants

EPHA3

1,318 papers

RefSeq Summary

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nerv...

Pfam Domains

Ephrin_lbdaa 30–202UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 203–259UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 263–306UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 327–426UCSCFibronectin type III domain

fn3aa 435–527UCSCFibronectin type III domain

EphA2_TMaa 543–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor A3

HGNC Previous Symbols

ETK; ETK1; TYRO4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005233.6

p.W86insFs

c.258dupG

Surrounding Variants

1 paper

NM_005233.6

p.W86*

c.257G>A

1 paper

NM_005233.6

p.N85T

c.254A>C

6 papers

NM_005233.6

p.N85S

c.254A>G

1 paper

NM_005233.6

p.W86*

c.258G>A

1 paper

NM_005233.6

p.V87I

c.259G>A

3 papers

NM_005233.6

p.V87L

c.259G>C

1 paper

NM_005233.6

p.T84T

c.252A>T

2 papers

NM_005233.6

p.T84A

c.250A>G

1 paper

NM_005233.6

p.P88T

c.262C>A

1 paper

NM_005233.6

p.P88H

c.263C>A

1 paper

NM_005233.6

p.P88L

c.263C>T

1 paper

NM_005233.6

p.R89S

c.267G>C