Varaico: Literature-Extracted Genetic Variants

EPHA3

1,318 papers

RefSeq Summary

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nerv...

Pfam Domains

Ephrin_lbdaa 30–202UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 203–259UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 263–306UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 327–426UCSCFibronectin type III domain

fn3aa 435–527UCSCFibronectin type III domain

EphA2_TMaa 543–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor A3

HGNC Previous Symbols

ETK; ETK1; TYRO4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005233.6

p.P110T

c.328C>A

Surrounding Variants

1 paper

NM_005233.6

p.P110P

c.330A>C

1 paper

NM_005233.6

p.I109L

c.325A>C

2 papers

NM_005233.6

p.V112D

c.335T>A

2 papers

NM_005233.6

p.V112V

c.336T>A

1 paper

NM_005233.6

p.V112V

c.336T>C

1 paper

NM_005233.6

p.C106*

c.318C>A

1 paper

NM_005233.6

p.C106S

c.317G>C

2 papers

NM_005233.6

p.G114R

c.340G>A

3 papers

NM_005233.6

p.G114R

c.340G>C

1 paper

NM_005233.6

p.G114*

c.340G>T

1 paper

NM_005233.6

p.C106S

c.316T>A

1 paper

NM_005233.6

p.G114E

c.341G>A