Varaico: Literature-Extracted Genetic Variants

EPHA3

1,318 papers

RefSeq Summary

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nerv...

Pfam Domains

Ephrin_lbdaa 30–202UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 203–259UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 263–306UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 327–426UCSCFibronectin type III domain

fn3aa 435–527UCSCFibronectin type III domain

EphA2_TMaa 543–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor A3

HGNC Previous Symbols

ETK; ETK1; TYRO4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005233.6

p.F152I

c.454T>A

Surrounding Variants

3 papers

NM_005233.6

p.F152L

c.454T>C

1 paper

NM_005233.6

p.F152S

c.455T>C

2 papers

NM_005233.6

p.F152L

c.456C>A

2 papers

NM_005233.6

p.F152L

c.456C>G

1 paper

NM_005233.6

p.T153A

c.457A>G

1 paper

NM_005233.6

p.T153S

c.457A>T

1 paper

NM_005233.6

p.T153S

c.458C>G

1 paper

NM_005233.6

p.E150K

c.448G>A

1 paper

NM_005233.6

p.D156N

c.466G>A

1 paper

NM_005233.6

p.L157I

c.469C>A

1 paper

NM_005233.6

p.L157V

c.469C>G

2 papers

NM_005233.6

p.A147T

c.439G>A