Varaico: Literature-Extracted Genetic Variants

EPHA3

1,318 papers

RefSeq Summary

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nerv...

Pfam Domains

Ephrin_lbdaa 30–202UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 203–259UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 263–306UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 327–426UCSCFibronectin type III domain

fn3aa 435–527UCSCFibronectin type III domain

EphA2_TMaa 543–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor A3

HGNC Previous Symbols

ETK; ETK1; TYRO4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005233.6

p.V759L

c.2275G>T

Surrounding Variants

3 papers

NM_005233.6

p.V759M

c.2275G>A

1 paper

NM_005233.6

p.V759L

c.2275G>C

1 paper

NM_005233.6

p.L758F

c.2274G>C

1 paper

NM_005233.6

p.L758F

c.2274G>T

1 paper

NM_005233.6

p.C760F

c.2279G>T

8 papers

NM_005233.6

p.K761N

c.2283G>C

8 papers

NM_005233.6

p.K761N

c.2283G>T

2 papers

NM_005233.6

p.S756I

c.2267G>T

1 paper

NM_005233.6

p.N755K

c.2265C>A

1 paper

NM_005233.6

p.N755K

c.2265C>G

1 paper

NM_005233.6

p.F765L

c.2293T>C

1 paper

NM_005233.6

p.F765L

c.2295C>A