Varaico: Literature-Extracted Genetic Variants

EPHA3

1,318 papers

RefSeq Summary

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nerv...

Pfam Domains

Ephrin_lbdaa 30–202UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 203–259UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 263–306UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 327–426UCSCFibronectin type III domain

fn3aa 435–527UCSCFibronectin type III domain

EphA2_TMaa 543–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor A3

HGNC Previous Symbols

ETK; ETK1; TYRO4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

10 papers

NM_005233.6

p.G766E

c.2297G>A

Surrounding Variants

1 paper

NM_005233.6

p.G766R

c.2296G>A

1 paper

NM_005233.6

p.G766R

c.2296G>C

1 paper

NM_005233.6

p.F765L

c.2295C>A

1 paper

NM_005233.6

p.L767I

c.2299C>A

1 paper

NM_005233.6

p.F765L

c.2295C>G

1 paper

NM_005233.6

p.F765F

c.2295C>T

1 paper

NM_005233.6

p.F765L

c.2293T>C

1 paper

NM_005233.6

p.S768T

c.2302T>A

3 papers

NM_005233.6

p.S768A

c.2302T>G

1 paper

NM_005233.6

p.S768L

c.2303C>T

1 paper

NM_005233.6

p.R769insFs

c.2305_2306ins5

1 paper

NM_005233.6

p.R769C

c.2305C>T