Varaico: Literature-Extracted Genetic Variants

EPHA3

1,318 papers

RefSeq Summary

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nerv...

Pfam Domains

Ephrin_lbdaa 30–202UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 203–259UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 263–306UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 327–426UCSCFibronectin type III domain

fn3aa 435–527UCSCFibronectin type III domain

EphA2_TMaa 543–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor A3

HGNC Previous Symbols

ETK; ETK1; TYRO4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005233.6

p.D806Y

c.2416G>T

Surrounding Variants

12 papers

NM_005233.6

p.D806N

c.2416G>A

1 paper

NM_005233.6

p.S805T

c.2414G>C

1 paper

NM_005233.6

p.S805I

c.2414G>T

1 paper

NM_005233.6

p.A804D

c.2411C>A

1 paper

NM_005233.6

p.A804V

c.2411C>T

1 paper

NM_005233.6

p.W808*

c.2423G>A

1 paper

NM_005233.6

p.W808S

c.2423G>C

2 papers

NM_005233.6

p.S803L

c.2408C>T

2 papers

NM_005233.6

p.T802R

c.2405C>G

1 paper

NM_005233.6

p.Y810F

c.2429A>T

3 papers

NM_005233.6

p.F801Y

c.2402T>A

1 paper

NM_005233.6

p.K800K

c.2400G>A