Varaico: Literature-Extracted Genetic Variants

EPHA3

1,318 papers

RefSeq Summary

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nerv...

Pfam Domains

Ephrin_lbdaa 30–202UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 203–259UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 263–306UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 327–426UCSCFibronectin type III domain

fn3aa 435–527UCSCFibronectin type III domain

EphA2_TMaa 543–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor A3

HGNC Previous Symbols

ETK; ETK1; TYRO4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005233.6

p.S906I

c.2717G>T

Surrounding Variants

1 paper

NM_005233.6

p.S906R

c.2716A>C

1 paper

NM_005233.6

p.S906G

c.2716A>G

1 paper

NM_005233.6

p.S906R

c.2718C>A

1 paper

NM_005233.6

p.S906R

c.2718C>G

1 paper

NM_005233.6

p.Q905K

c.2713C>A

1 paper

NM_005233.6

p.D909V

c.2726A>T

1 paper

NM_005233.6

p.I910V

c.2728A>G

1 paper

NM_005233.6

p.L903del1

c.2707_2709delCTG

1 paper

NM_005233.6

p.L901H

c.2702T>A

1 paper

NM_005233.6

p.N900K

c.2700C>A

1 paper

NM_005233.6

p.N900K

c.2700C>G

1 paper

NM_005233.6

p.F913I

c.2737T>A