Varaico: Literature-Extracted Genetic Variants

EPHA3

1,318 papers

RefSeq Summary

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nerv...

Pfam Domains

Ephrin_lbdaa 30–202UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 203–259UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 263–306UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 327–426UCSCFibronectin type III domain

fn3aa 435–527UCSCFibronectin type III domain

EphA2_TMaa 543–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor A3

HGNC Previous Symbols

ETK; ETK1; TYRO4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005233.6

p.N921Y

c.2761A>T

Surrounding Variants

1 paper

NM_005233.6

p.L920H

c.2759T>A

1 paper

NM_005233.6

p.W919*

c.2757G>A

1 paper

NM_005233.6

p.W919*

c.2756G>A

1 paper

NM_005233.6

p.D918H

c.2752G>C

1 paper

NM_005233.6

p.D918Y

c.2752G>T

14 papers

NM_005233.6

p.W924R

c.2770T>A

14 papers

NM_005233.6

p.W924R

c.2770T>C

1 paper

NM_005233.6

p.W924*

c.2771G>A

2 papers

NM_005233.6

p.W924*

c.2772G>A

1 paper

NM_005233.6

p.W924C

c.2772G>C

1 paper

NM_005233.6

p.W924C

c.2772G>T

1 paper

NM_005233.6

p.T915I

c.2744C>T