Varaico: Literature-Extracted Genetic Variants

EPHA4

232 papers

RefSeq Summary

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nerv...

Pfam Domains

Ephrin_lbdaa 31–204UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 205–262UCSCEphrin cysteine rich domain

fn3aa 328–431UCSCFibronectin type III domain

fn3aa 439–531UCSCFibronectin type III domain

EphA2_TMaa 549–618UCSCEphrin type-A receptor 2 transmembrane domain

PK_Tyr_Ser-Thraa 621–878UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

EPH receptor A4

HGNC Previous Symbol

TYRO1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004438.5

p.D773N

c.2317G>A

Surrounding Variants

1 paper

NM_004438.5

p.E772Q

c.2314G>C

1 paper

NM_004438.5

p.P775T

c.2323C>A

3 papers

NM_004438.5

p.P775L

c.2324C>T

1 paper

NM_004438.5

p.V770G

c.2309T>G

1 paper

NM_004438.5

p.F765S

c.2294T>C

1 paper

NM_004438.5

p.T781A

c.2341A>G

2 papers

NM_004438.5

p.C760R

c.2278T>C

1 paper

NM_004438.5

p.S756R

c.2268C>G

1 paper

NM_004438.5

p.S756R

c.2268C>A

1 paper

NM_004438.5

p.S756R

c.2266A>C

1 paper

NM_004438.5

p.A748V

c.2243C>T

1 paper

NM_004438.5

p.A748T

c.2242G>A