Varaico: Literature-Extracted Genetic Variants

EPHA4

232 papers

RefSeq Summary

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nerv...

Pfam Domains

Ephrin_lbdaa 31–204UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 205–262UCSCEphrin cysteine rich domain

fn3aa 328–431UCSCFibronectin type III domain

fn3aa 439–531UCSCFibronectin type III domain

EphA2_TMaa 549–618UCSCEphrin type-A receptor 2 transmembrane domain

PK_Tyr_Ser-Thraa 621–878UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

EPH receptor A4

HGNC Previous Symbol

TYRO1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004438.5

p.A94T

c.280G>A

Surrounding Variants

1 paper

NM_004438.5

p.A94V

c.281C>T

1 paper

NM_004438.5

p.G93A

c.278G>C

1 paper

NM_004438.5

p.Q95E

c.283C>G

1 paper

NM_004438.5

p.E92K

c.274G>A

1 paper

NM_004438.5

p.R91Q

c.272G>A

1 paper

NM_004438.5

p.W88C

c.264G>T

1 paper

NM_004438.5

p.W88C

c.264G>C

1 paper

NM_004438.5

p.K102*

c.304A>T

1 paper

NM_004438.5

p.R85Q

c.254G>A

1 paper

NM_004438.5

p.L84L

c.250C>T

1 paper

NM_004438.5

p.Q80R

c.239A>G

1 paper

NM_004438.5

p.E77D

c.231A>T