Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017449.5

p.M1insFs

c.2_3insG

Surrounding Variants

3 papers

NM_017449.5

p.M1T

c.2T>C

1 paper

NM_017449.5

p.M1Fs

c.2delinsCTGFs

1 paper

NM_017449.5

p.M1R

c.2T>G

1 paper

NM_017449.5

p.A2delFs

c.4delG

3 papers

NM_017449.5

p.M1insFs

c.2_3insT

2 papers

NM_017449.5

p.M1L

c.1A>C

2 papers

NM_017449.5

p.M1V

c.1A>G

2 papers

NM_017449.5

p.M1L

c.1A>T

2 papers

NM_017449.5

p.M1I

c.3G>A

1 paper

NM_017449.5

p.M1I

c.3G>C

1 paper

NM_017449.5

p.M1I

c.3G>T

1 paper

NM_017449.5

p.R4Q

c.11G>A